HAITAO LU GROUP

Peer-Reviewed Publications

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44. Hu, L., Liu, J., Zhang, W., Wang, T., Zhang, N., Lee, HK. and Lu*. (2019). Functional metabolomics decipher biochemical functions and associated mechanisms underlie small-molecule metabolism. Mass Spectrometry Reviews, Just be Accepted (Invited by Editor in Chief) (*Corresponding Author)
43. Lu, H*. Que, Y., Wu, X., Guan, T. and Guo, H. (2019). Mass Spectrometry based Metabolomics Deciphered Metabolic Reprogramming That Was Required for Biofilm formation in Uropathogenic Escherichia coli. Scientific Reports, 9(1): 13160. (*Corresponding Author)
42. Xu, G., Guo, H., and Lv, H*. (2019). Metabolomics Assay Identified a Novel Virulence-Associated Siderophore Encoded by the High-Pathogenicity Island in Uropathogenic Escherichia coli (correction). J Proteome Res., 18, 2331-2336. (*Corresponding Author)
41. Luo, X., Guo, R., Xu, X., Li, X., Yao, L., Wang, X., and Lu, H*. (2019). Spectrometry and Associated Technologies Delineate The Advantageously Biomedical Capacity Of Siderophores In Different Pathogenic Contexts. Mass Spectrometry Reviews, 38, 239-252 (Invited by Editor in Chief)(*Corresponding Author)
40. Cui, L., Lu, H. and Lee, Y.H. (2018). Challenges and emergent solutions for LC-MS/MS based untargeted metabolomics in diseases. Mass Spectrometry Reviews, 37, 772-792.
39. Su, Q, Xu, G. Guan, T. Que, Y, and Lu, H*. (2018). Mass spectrometry-derived systems biology technologies delineate the system’s applications of siderophores with chemistry and biology. Mass Spectrometry Reviews, 37, 188-201 (Invited by Editor in Chief) (*Corresponding Author)
38. Lv, Y., Que, Y., Su, Q., Li, Q., and Lu, H*. (2016). Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy. Oncotarget, doi: 10.18632/oncotarget.10586. (*Corresponding Author)
37. Su, Q., Guan, T. B., He, Y. and Lv, H*. (2016). Siderophore biosynthesis governs the virulence of uropathogenic Escherichia coli by coordinately modulating the differential metabolism. Journal of Proteome Research, 15 , 1323–1332. (*Corresponding Author)
36. Su, Q., Guan, T. and Lv, H*. (2016) Siderophore biosynthesis coordinately modulated the virulence associated interactive metabolome of uropathogenic Escherichia coli and human urine. Scientific Reports, 6, 24099; doi: 10.1038/srep24099 (*Corresponding Author)
35. Nie, W.N., Yan, L. Y. Lee, Y. H., Guha, C., Kurland, I. J., and Lu, H.T.,* (2016). Advanced mass spectrometry based multiple omics technologies for exploring the pathogenesis of hepatocellular carcinoma. Mass Spectrometry Reviews, 35, 331-349. (*Corresponding Author)
34. Zang, T., Broszczak, D. A., Broadbent, J. A., Cuttle, L., Lu, H., Parker T. J. (2016). The biochemistry of blister fluid from pediatric burn injuries: proteomics and metabolomics aspects. Expert Rev Proteomics., 13, 35-53
33. Nie, W., Lv, Y., Yan, L., Chen, X. and Lv, H*. (2015): Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms. Scientific Reports 5, 17646; doi: 10.1038/srep17646. (*Corresponding Author)
32. Yan L, Nie W, Lu, H.T.*（2015）Metabolic phenotyping of the Yersinia high-pathogenicity island that regulates central carbon metabolism. Analyst. 2015;140(10):3356-3361.(*Corresponding Author)
31. Nie, W. N., Lv, Y. N., Yan, L. Y., Guan, T. B., Li, Q., Guo, X. J., Liu, W. H., Feng, M. P., Xu, G., Chen, X., Lu, H.T.* (2015) Discovery and Characterization of Disease Risk Functional Modules and Pathogenic Genes of Coronary Artery Disease. RSC Advances, 5, 26443-26451. (*Corresponding Author)
30. Liu, W. H., Guo, X. J., Li, Q., Xu, G., Feng, M. P., Guan, T. B., Yan, L. Y., Nie, W. N., Parker, T., Lu, H.T.*Mass Spectrometry Based Molecular Profile Dissects the Complexity of Traditional Chinese Medicine. Anal Methods, 2015, DOI: 10.1039/C4AY02991G.(*Corresponding Author)
29. Wang, X.J*., Lv, H.T.,Zhang, A. H., Wenjun Sun, Liu, L., Wang, P., Wu, Z.M., Zhou, D. X., Sun, H. * (2014) Metabolite profiling and pathway analysis of acute hepatitis rats by UPLC-ESI MS combined with pattern recognition methods. Liver International, 34, 759-770.
28. Lv, H. T*., Hung, C. S., and Henderson, J. P.* (2014): Metabolomic Analysis of Siderophore Cheater Mutants Reveals Metabolic Costs of Expression in Uropathogenic Escherichia coli.Journal of Proteome Research, 13, 1397-1404. (*Corresponding Author)
27. Lv, H. T.* (2013): Mass spectrometry based metabolomics towards understanding of gene functions with a diversity of biological contexts, Mass Spectrometry Reviews, 32,118-128. (*Corresponding Author).
26. Yan, L. Y., Nie, W.N., Parker, T., Upton, Z., Lu, H. T. *(2013) Mass spectrometry based metabolomics facilitates the discovery of in vivo functional small-molecules with a diversity of biological contexts. Future Medicinal Chemistry, 5, 1953-1965. (*corresponding author)
25. Wang, P.,Lv, H. T., Zhang, A. H., Sun, H., Yan, G.L., Han, Y., Wu, X. H., Wang, X. J. (2013) Improved ultra-performance liquid chromatography with electrospray ionization quadrupole-time-of-flight high-definition mass spectrometry method for the rapid analysis of the chemical constituents of a typical medical formula: Liuwei Dihuang Wan. J Sep Sci. 36, 3511-3516.
24. Wang. X.J.,* Zhang, A.H., Wang, P., Sun, H., Wu, G., Sun, W.J., Lv, H.T.,et al. (2013): Metabolomics coupled with proteomics advancing drug discovery towards more agile development of targeted combination therapies.Mol Cell Proteomics. 12, 1226-1238.
23. Sun, H., Li, L. J., Zhang, A.H., Zhang, N., Lv, H.T.,Sun. W.J., Wang, X.J.* (2013): Protective effects of sweroside on human MG-63 cells and rat osteoblasts. Fitoterapia.84, 174-179.
22. Lu, H.T.*(2012): Who is linking Macro- Imaging Technique to Real Micro-Biological World ? J Bioequiv Availab4: 2. (Editorial) (*Corresponding Author).
21. Lv, H.T., and Henderson, J. P. (2011): YersiniaHigh Pathogenicity Island genes modify The Escherichia coli primary metabolome independently of siderophore production. Journal Proteome Research,10, 5547–5554.
20. Lv, H.T*., Hung, C. S., Chaturvedi, K. S., Hooton, T. M., and Henderson, J.P.* (2011):Development of an integrated metabolomic approach for Infectious Diseases Research. Analyst, 136, 4752-4763. (*Corresponding Author).
19. Lv, H.T.,Palacios, G., Hartil, K. and Kurland, I.J. (2011):Advantages of Tandem LC-MS for the Rapid Assessment of Tissue-specific Metabolic Complexity using a Pentafluorophenylpropyl Stationary Phase. Journal Proteome Research, 10, 2104-2012.
18. Lv, H.T*., Liu, L., Palacios, G. and Chen, X. (2011): Metabolomic Analysis Characterizes Tissue Specific Metabolic Perturbations of the Rats Induced by Indomethacin. Analyst,136, 2260-2269.(*Corresponding Author).
17. Lv, H.T*., Liu, L, Zhang, Y.Z., Song, T., Lu, J. and Chen, X. (2010) Ingenuity Pathways Analysis of Urine Metabonomics Phenotypes Toxicity of Gentamicin in Multiple Organs. Molecular BioSystems 2010, 6, 2056-2067. (*Corresponding Author)
16. Chen, X., Liu, L., Palacios, G., Gao, J., Zhang, N., Li, G., Lu, J., Song, T., Zhang, Y.Z. andLv, H.T.*. Plasma Metabolomics Reveals Biomarkers of Atherosclerosis. Journal of Separation Science 2010, 33, 2776-2783. (*Corresponding Author)
15. Wang, P., Sun, H., Lv, H.T., Sun, W.J., Yuan, Y., Han, Y., Wang, D.W., Zhang, A.H. and Wang, X.J. (2010): Thyroxine and reserpine-induced changes in metabolic profiles of rat urine and the therapeutic effect of Liu Wei Di Huang Wan detected by UPLC-HDMS. Journal of Pharmaceutical and Biomedical Analysis, 53, 631-645.
14. Cao, H.X., Chen, X., Sun, H., Sakurai, T., Zhou, J., Sun, W.J., Lv, H.T. and Wang, X.J. (2010): Pharmacokinetics-Based Elucidation on Disparity in Clinical Effectiveness Between Varieties of Zhi Zhu Wan, a Traditional Chinese Medical Formula. J Ethnopharmacol. 128, 606-610.
13. Cao, H.X., Sun, H., Jiang, X.G.,Lv, H.T., Zhang, G.M., Wang, X.J., Sun, W.J., Wu, Z.M., Wang, P., Liu, L. and Zhou, J. (2009): Comparative Studies on the Protective Effects of Yinchenhao Decoction against Liver Injury Induced by ANIT and CCL4. Chinese Journal of Integrative Medicine 15, 204-209.
12. Lv, H.T., Sun, H., Wang, X.J*., Sun, W.J., Jiao, G.Z., Zhou, D.X., Zhao, L. and Zhang, G.M. (2008): Simultaneous determination by UPLC-ESI-MS of scoparone, capillarisin, rhein, and emodin in rat urine after oral administration of Yin Chen Hao Tang preparation. Journal of Separation Science 31, 659-666.
11. Lv, H.T., Sun, H., Sun, W.J., Liu, L., Wang, P., Wang, and X.J*., and Cao, H.X. (2008) Pharmacokinetic studies of a Chinese triple herbal drug formula. Phytomedicine 15, 993-1001.
10. Wang, X.J*., Lv, H.T., Sun, H., Liu, L., Yang, B., Sun, W.J., Wang, P., Zhou, D.X., Zhao, L., Dou, S.S., Zhang, G.M. and Cao, H.X. (2008): Metabolic urinary profiling of alcohol hepatotoxicity and intervention effects of Yin Chen Hao Yang in rats using ultra- performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 48, 1161-1168.
9. Wang, X.J*., Lv, H.T., Zhang, G.M., Sun, W.J., Zhou, D.X., Jiao, G.Z. and Yu, Y. (2008): Development and validation of a UPLC-ESI/MS method for analysis of metabolic phenotypes of healthy men in day and night. Journal of Separation Science, 31, 2994-3001.
8. Wang, X.J*., Lv, H.T., Sun, H., Sun, W.J., Liu, L., Wang, P. and Cao, H.X. (2008): Simultaneous determination of 6, 7-dimethylesculetin and geniposide in rat plasma and its application for pharmacokinetic studies of Yin Chen Hao Tang preparation. Arzneimittel-Forschung/Drug Research 58, 336-341.
7. Wang, X.J*., Lv, H.T., Sun, H., Jiang, X.G., Wu, Z.M., Wang, P., Liu, L. and Cao, H.X. (2008): Quality evaluation of Yin Chen Hao Tang extract based on fingerprint chromatogram and simultaneous determination of five bioactive constituents. Journal of Separation Science 31, 9-15.
6. Wang, X.J*., Sun, W.J., Sun, H., Lv, H.T., Wu, Z.M., Wang, P., Liu, L. and Cao, H.X. (2008): Analysis of the constituents in the rat plasma after oral administration of Yin Chen Hao Tang by UPLC/Q-TOF-MS/MS. Journal of Pharmaceutical and Biomedical Analysis 46, 477-490.
5. Wang, X.J*., Wang, Z.H., Sun, H., Lv, H.T., Guan, H.Y., Meng, X.C., Sun, H.F., Zhang, G.M. and Cao, H.X. (2008): Pharmacokinetics of cimifugin in rat plasma after oral administration of the extract of saposhnikovia divaricatae root / determination of cimifugin by high performance liquid chromatography coupled with solid phase extraction. Arzneimittel-Forschung/Drug Research 58, 445-450.
4. Wang, X.J*., Lv, H.T., Sun, H., Liu, L., Sun, W.J. and Cao, H.X. (2007) : Development of a rapid and validated method for investigating the metabolism of scoparone in rat using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 21, 3883-3890.
3. Sun, H., Lv, H.T., Zhang, Y.M., Wang, X.J*., Bi, K.S. and Cao, H.X. (2007): Pharmacokinetics of isofraxidin in rat plasma after oral administration of the extract of acanthopanax senticosus using HPLC with solid phase extraction method. Chemical and Pharmaceutical Bulletin 55, 1291-1295.
2. Sun, H., Lv, H.T., Zhang, Y.M., Meng, X.C., Sui, J.T., Wang, X.J*. and Bi, K.S. (2007): HPLC method for preliminary analysis of constituents in rat blood after oral administration of the extract of acanthopanax senticosus. Journal of Separation Science 30, 3120-3126.
1. Sun, H., Lv, H.T., Zhang, Y.M., Wang, X.J*., Bi, K.S. and Cao, H.X. (2007): A rapid and sensitive UPLC-ESI MS method for analysis of isofraxidin, a natural anti-stress compound, its metabolites in rat plasma. Journal of Separation Science30, 3202-3206.